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Biochemical Mechanisms Leading to Tryptophan 2,3-Dioxygenase Activation

Tryptophan 2,3-dioxygenase (TDO) is the first enzyme in the tryptophan oxidation pathway. It is a hemoprotein and its heme prosthetic group is present as a heme-ferric (heme-Fe(3+)) form that is not active. To be able to oxidize tryptophan, the heme-Fe(3+) form of the enzyme must be reduced to a hem...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Junsuo S., Han, Qian, Fang, Jianmin, Rizzi, Menico, James, Anthony A., Li, Jianyong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565576/
https://ncbi.nlm.nih.gov/pubmed/17212352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/arch.20159
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