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Transcriptional Control of Brown Fat Determination by PRDM16

Brown fat cells are specialized to dissipate energy and can counteract obesity; however, the transcriptional basis of their determination is largely unknown. We show here that the zinc-finger protein PRDM16 is highly enriched in brown fat cells compared to white fat cells. When expressed in white fa...

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Detalhes bibliográficos
Main Authors: Seale, Patrick, Kajimura, Shingo, Yang, Wenli, Chin, Sherry, Rohas, Lindsay, Uldry, Marc, Tavernier, Geneviève, Langin, Dominique, Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564846/
https://ncbi.nlm.nih.gov/pubmed/17618855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.06.001
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