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Initiation of myoblast/brown fat switch through a PRDM16-C/EBP-β transcriptional complex

Brown adipose cells are specialized to dissipate chemical energy in the form of heat, as a physiological defense against cold and obesity1. PRDM16 (PRD1-BF1-RIZ1 homologous domain containing 16) is a 140 kDa zinc finger protein that robustly induces brown fat determination and differentiation2. Rece...

詳細記述

保存先:
書誌詳細
主要な著者: Kajimura, Shingo, Seale, Patrick, Kubota, Kazuishi, Lunsford, Elaine, Frangioni, John V., Gygi, Steven P., Spiegelman, Bruce M.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754867/
https://ncbi.nlm.nih.gov/pubmed/19641492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08262
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