Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

Brown fat is a specialized tissue that can dissipate energy and counteract obesity through a pattern of gene expression that greatly increases mitochondrial content and uncoupled respiration. PRDM16 is a zinc-finger protein that controls brown fat determination by stimulating brown fat-selective gen...

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Detalhes bibliográficos
Main Authors: Kajimura, Shingo, Seale, Patrick, Tomaru, Takuya, Erdjument-Bromage, Hediye, Cooper, Marcus P., Ruas, Jorge L., Chin, Sherry, Tempst, Paul, Lazar, Mitchell A., Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377193/
https://ncbi.nlm.nih.gov/pubmed/18483224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1666108
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