Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma

The purpose of this study is to estimate the maximum-tolerated dose (MTD) and describe toxicities and preliminary clinical effects of tipifarnib, a farnesyltransferase (FTase) inhibitor, administered concurrently with radiation therapy in children with newly diagnosed intrinsic diffuse brainstem gli...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Haas-Kogan, Daphne A., Banerjee, Anuradha, Kocak, Mehmet, Prados, Michael D., Geyer, J. Russell, Fouladi, Maryam, McKnight, Tracy, Poussaint, Tina Young, Broniscer, Alberto, Blaney, Susan M., Boyett, James M., Kun, Larry E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Duke University Press 2008
Θέματα:
Clinical Investigations
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563056/
https://ncbi.nlm.nih.gov/pubmed/18417739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-004
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