Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma

The purpose of this study is to estimate the maximum-tolerated dose (MTD) and describe toxicities and preliminary clinical effects of tipifarnib, a farnesyltransferase (FTase) inhibitor, administered concurrently with radiation therapy in children with newly diagnosed intrinsic diffuse brainstem gli...

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Detalhes bibliográficos
Main Authors: Haas-Kogan, Daphne A., Banerjee, Anuradha, Kocak, Mehmet, Prados, Michael D., Geyer, J. Russell, Fouladi, Maryam, McKnight, Tracy, Poussaint, Tina Young, Broniscer, Alberto, Blaney, Susan M., Boyett, James M., Kun, Larry E.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2008
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563056/
https://ncbi.nlm.nih.gov/pubmed/18417739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-004
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