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Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma

The purpose of this study is to estimate the maximum-tolerated dose (MTD) and describe toxicities and preliminary clinical effects of tipifarnib, a farnesyltransferase (FTase) inhibitor, administered concurrently with radiation therapy in children with newly diagnosed intrinsic diffuse brainstem gli...

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書誌詳細
主要な著者: Haas-Kogan, Daphne A., Banerjee, Anuradha, Kocak, Mehmet, Prados, Michael D., Geyer, J. Russell, Fouladi, Maryam, McKnight, Tracy, Poussaint, Tina Young, Broniscer, Alberto, Blaney, Susan M., Boyett, James M., Kun, Larry E.
フォーマット: Artigo
言語:Inglês
出版事項: Duke University Press 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563056/
https://ncbi.nlm.nih.gov/pubmed/18417739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-004
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