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Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma
The purpose of this study is to estimate the maximum-tolerated dose (MTD) and describe toxicities and preliminary clinical effects of tipifarnib, a farnesyltransferase (FTase) inhibitor, administered concurrently with radiation therapy in children with newly diagnosed intrinsic diffuse brainstem gli...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Duke University Press
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2563056/ https://ncbi.nlm.nih.gov/pubmed/18417739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-004 |
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