Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma

The purpose of this study is to estimate the maximum-tolerated dose (MTD) and describe toxicities and preliminary clinical effects of tipifarnib, a farnesyltransferase (FTase) inhibitor, administered concurrently with radiation therapy in children with newly diagnosed intrinsic diffuse brainstem gli...

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Dades bibliogràfiques
Autors principals: Haas-Kogan, Daphne A., Banerjee, Anuradha, Kocak, Mehmet, Prados, Michael D., Geyer, J. Russell, Fouladi, Maryam, McKnight, Tracy, Poussaint, Tina Young, Broniscer, Alberto, Blaney, Susan M., Boyett, James M., Kun, Larry E.
Format: Artigo
Idioma:Inglês
Publicat: Duke University Press 2008
Matèries:
Clinical Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563056/
https://ncbi.nlm.nih.gov/pubmed/18417739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-004
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