Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas

We performed a phase II study to assess the efficacy and toxicity of tipifarnib, a farnesyltransferase inhibitor, administered with radiation therapy (RT) in children with newly diagnosed diffuse intrinsic pontine gliomas. Children 3-21 years old with pontine gliomas (BSGs) were treated with concurr...

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Bibliographische Detailangaben
Hauptverfasser: Haas-Kogan, Daphne A., Banerjee, Anuradha, Poussaint, Tina Young, Kocak, Mehmet, Prados, Michael D., Geyer, J. Russell, Fouladi, Maryam, Broniscer, Alberto, Minturn, Jane E., Pollack, Ian F., Packer, Roger J., Boyett, James M., Kun, Larry E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Clinical Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064607/
https://ncbi.nlm.nih.gov/pubmed/21339191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq202
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