Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas

We performed a phase II study to assess the efficacy and toxicity of tipifarnib, a farnesyltransferase inhibitor, administered with radiation therapy (RT) in children with newly diagnosed diffuse intrinsic pontine gliomas. Children 3-21 years old with pontine gliomas (BSGs) were treated with concurr...

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Main Authors: Haas-Kogan, Daphne A., Banerjee, Anuradha, Poussaint, Tina Young, Kocak, Mehmet, Prados, Michael D., Geyer, J. Russell, Fouladi, Maryam, Broniscer, Alberto, Minturn, Jane E., Pollack, Ian F., Packer, Roger J., Boyett, James M., Kun, Larry E.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
主題:
Clinical Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064607/
https://ncbi.nlm.nih.gov/pubmed/21339191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq202
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