Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas

We performed a phase II study to assess the efficacy and toxicity of tipifarnib, a farnesyltransferase inhibitor, administered with radiation therapy (RT) in children with newly diagnosed diffuse intrinsic pontine gliomas. Children 3-21 years old with pontine gliomas (BSGs) were treated with concurr...

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Dettagli Bibliografici
Autori principali: Haas-Kogan, Daphne A., Banerjee, Anuradha, Poussaint, Tina Young, Kocak, Mehmet, Prados, Michael D., Geyer, J. Russell, Fouladi, Maryam, Broniscer, Alberto, Minturn, Jane E., Pollack, Ian F., Packer, Roger J., Boyett, James M., Kun, Larry E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Clinical Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064607/
https://ncbi.nlm.nih.gov/pubmed/21339191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq202
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