Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas

We performed a phase II study to assess the efficacy and toxicity of tipifarnib, a farnesyltransferase inhibitor, administered with radiation therapy (RT) in children with newly diagnosed diffuse intrinsic pontine gliomas. Children 3-21 years old with pontine gliomas (BSGs) were treated with concurr...

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Bibliografiska uppgifter
Huvudupphovsmän: Haas-Kogan, Daphne A., Banerjee, Anuradha, Poussaint, Tina Young, Kocak, Mehmet, Prados, Michael D., Geyer, J. Russell, Fouladi, Maryam, Broniscer, Alberto, Minturn, Jane E., Pollack, Ian F., Packer, Roger J., Boyett, James M., Kun, Larry E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2011
Ämnen:
Clinical Investigations
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064607/
https://ncbi.nlm.nih.gov/pubmed/21339191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq202
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