Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma

The purpose of this study is to estimate the maximum-tolerated dose (MTD) and describe toxicities and preliminary clinical effects of tipifarnib, a farnesyltransferase (FTase) inhibitor, administered concurrently with radiation therapy in children with newly diagnosed intrinsic diffuse brainstem gli...

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Bibliografske podrobnosti
Main Authors: Haas-Kogan, Daphne A., Banerjee, Anuradha, Kocak, Mehmet, Prados, Michael D., Geyer, J. Russell, Fouladi, Maryam, McKnight, Tracy, Poussaint, Tina Young, Broniscer, Alberto, Blaney, Susan M., Boyett, James M., Kun, Larry E.
Format: Artigo
Jezik:Inglês
Izdano: Duke University Press 2008
Teme:
Clinical Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563056/
https://ncbi.nlm.nih.gov/pubmed/18417739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-004
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