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ABSENCE OF CARBOXYPEPTIDASE E LEADS TO ADULT HIPPOCAMPAL NEURONAL DEGENERATION AND MEMORY DEFICITS

Molecules that govern the formation, integrity and function of the hippocampus remain an important area of investigation. Here we show that absence of the proneuropeptide processing enzyme, carboxypeptidase E (CPE) in CPE knock-out (KO) mice had a profound effect on memory, synaptic physiology and t...

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Detalhes bibliográficos
Main Authors: Woronowicz, Alicja, Koshimizu, Hisatsugu, Chang, Su-Youne, Cawley, Niamh X., Hill, Joanna M., Rodriguiz, Ramona M., Abebe, Daniel, Dorfman, Caroline, Senatorov, Vladimir, Zhou, An, Xiong, Zhi-Gang, Wetsel, William C., Loh, Y. Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562794/
https://ncbi.nlm.nih.gov/pubmed/18570185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20462
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