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CARBOXYPEPTIDASE E KNOCK-OUT MICE EXHIBIT ABNORMAL DENDRITIC ARBORIZATION AND SPINE MORPHOLOGY IN CNS NEURONS

Carboxypeptidase E (CPE) is involved in maturation of neuropeptides and sorting of brain-derived neurotrophic factor (BDNF) to the regulated pathway for activity-dependent secretion from CNS neurons. CPE knock-out (CPE-KO) mice have many neurological deficits including learning and memory. Here, we...

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Detalhes bibliográficos
Main Authors: Woronowicz, Alicja, Cawley, Niamh X., Chang, Su-Youne, Koshimizu, Hisatsugu, Phillips, André W., Xiong, Zhi-Gang, Loh, Y. Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844261/
https://ncbi.nlm.nih.gov/pubmed/19598241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22174
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