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A Bi-directional Carboxypeptidase E - driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons

Anterograde transport of brain-derived neurotrophic factor (BDNF) vesicles from the soma to neurite terminals is necessary for activity-dependent secretion of BDNF to mediate synaptic plasticity, memory and learning, and retrograde BDNF transport back to the soma for recycling. In our study, overexp...

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Detalhes bibliográficos
Main Authors: Park, Joshua J., Cawley, Niamh X., Loh, Y. Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606928/
https://ncbi.nlm.nih.gov/pubmed/18573344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.05.016
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