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Carboxypeptidase E Cytoplasmic Tail-Driven Vesicle Transport Is Key for Activity-Dependent Secretion of Peptide Hormones

Vesicular transport of peptide hormones from the cell body to the plasma membrane for activity-dependent secretion is important for endocrine function, but how it is achieved is unclear. Here we uncover a mechanism in which the cytoplasmic tail of transmembrane carboxypeptidase E (CPE) found in proo...

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Detalhes bibliográficos
Main Authors: Park, Joshua J., Cawley, Niamh X., Loh, Y. Peng
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276472/
https://ncbi.nlm.nih.gov/pubmed/18202146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0473
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