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Thrombospondin-1 is a Central Regulator of Nitric Oxide Signaling in Vascular Physiology

Thrombospondin-1 is secreted protein that modulates vascular cell behavior via several cell surface receptors. In vitro, nanomolar concentrations of thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. Yet, much lower lev...

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Main Authors: Isenberg, Jeff S., Frazier, William A., Roberts, David D.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562780/
https://ncbi.nlm.nih.gov/pubmed/18193160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-007-7488-x
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