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Probing Structural Differences in Prion Protein Isoforms by Tyrosine Nitration

Two conformational isomers of recombinant hamster prion protein (residues 90-232) have been probed by reaction with two tyrosine nitration reagents, peroxynitrite and tetranitromethane. Two conserved tyrosine residues (tyrosines 149 and 150) are not labeled by either reagent in the normal cellular f...

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Detalhes bibliográficos
Main Authors: Lennon, Christopher W., Cox, Holly D., Hennelly, Scott P., Chelmo, Sam J., McGuirl, Michele A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562509/
https://ncbi.nlm.nih.gov/pubmed/17397138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0617254
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