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Glycosylation differences between the normal and pathogenic prion protein isoforms

Prion protein consists of an ensemble of glycosylated variants or glycoforms. The enzymes that direct oligosaccharide processing, and hence control the glycan profile for any given glycoprotein, are often exquisitely sensitive to other events taking place within the cell in which the glycoprotein is...

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Detalhes bibliográficos
Main Authors: Rudd, Pauline M., Endo, Tama, Colominas, Cristina, Groth, Darlene, Wheeler, Susan F., Harvey, David J., Wormald, Mark R., Serban, Hana, Prusiner, Stanley B., Kobata, Akira, Dwek, Raymond A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23897/
https://ncbi.nlm.nih.gov/pubmed/10557270
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