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Structural Organization of Mammalian Prions as Probed by Limited Proteolysis

Elucidation of the structure of PrP(Sc) continues to be one major challenge in prion research. The mechanism of propagation of these infectious agents will not be understood until their structure is solved. Given that high resolution techniques such as NMR or X-ray crystallography cannot be used, a...

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Detalhes bibliográficos
Main Authors: Vázquez-Fernández, Ester, Alonso, Jana, Pastrana, Miguel A., Ramos, Adriana, Stitz, Lothar, Vidal, Enric, Dynin, Irina, Petsch, Benjamin, Silva, Christopher J., Requena, Jesús R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502352/
https://ncbi.nlm.nih.gov/pubmed/23185550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050111
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