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Improved Chemical Syntheses of 5,6-Dihydro-5-fluorouracil

[Image: see text] 5,6-Dihydro-5-fluorouracil (5-DHFU) is a metabolite of the chemotherapy drug 5-fluorouracil (5-FU) of importance for biological studies. 5-DHFU has been prepared by enzymatic reduction of 5-FU and in very low yield by hydrogenation of 5-FU; however, a practical chemical synthesis i...

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Bibliografiska uppgifter
Huvudupphovsmän: LaFrate, Andrew L., Katzenellenbogen, John A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562335/
https://ncbi.nlm.nih.gov/pubmed/17900141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo071255z
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