The effects of 5R-5,6-dihydro-5-hydroxythymidine on duplex DNA stability and structure.

An improved method for the chemical synthesis of oligodeoxynucleotides containing 5 R -5,6-dihydro-5-hydroxythymidine (1) at a defined site is reported. UV melting studies carried out on duplexes containing1synthesized in this manner correlate with previously reported enzyme inhibition experiments,...

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Bibliographic Details
Main Authors: Sambandam, A, Greenberg, M M
Format: Artigo
Language:Inglês
Published: 1999
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC148606/
https://ncbi.nlm.nih.gov/pubmed/10446252
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