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6-Thioguanine alters the structure and stability of duplex DNA and inhibits quadruplex DNA formation.

The ability to chemically synthesize biomolecules has opened up the opportunity to observe changes in structure and activity that occur upon single atom substitution. In favorable cases this can provide information about the roles of individual atoms. The substitution of 6-thioguanine (6SG) for guan...

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Bibliografiske detaljer
Main Authors: Marathias, V M, Sawicki, M J, Bolton, P H
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC148499/
https://ncbi.nlm.nih.gov/pubmed/10390526
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