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Impact of PKM Linkers on Biodistribution Characteristics of the (99m)Tc-Labeled Cyclic RGDfK Dimer

This report describes synthesis of three new cyclic RGDfK peptide conjugates, HYNIC-PKM-SU016 (PKM = E, K and PEG4), and in vivo evaluation of the impact of PKM linkers on biodistribution characteristics of their ternary ligand complexes [(99m)Tc(HYNIC-PKM-SU016)(tricine)(TPPTS)] in athymic nude mic...

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Detalhes bibliográficos
Main Authors: Liu, Shuang, He, Zhengjie, Hsieh, Wen-Yuan, Kim, Young-Seung, Jiang, Young
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562319/
https://ncbi.nlm.nih.gov/pubmed/17105229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc060235l
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