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Evaluation of (99m)Tc-Labeled Cyclic RGD Dimers: Impact of Cyclic RGD Peptides and (99m)Tc Chelates on Biological Properties

The main objective of this study is to explore the impact of cyclic RGD peptides and (99m)Tc chelates on biological properties of (99m)Tc radiotracers. Cyclic RGD peptide conjugates, HYNIC-K(NIC)-RGD(2) (HYNIC = 6-hydrazinonicotinyl; RGD(2) = E[c(RGDfK)](2) and NIC = nicotinyl) HYNIC-K(NIC)-3G-RGD(2...

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Detalhes bibliográficos
Main Authors: Zhou, Yang, Kim, Young-Seung, Lu, Xin, Liu, Shuang
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310279/
https://ncbi.nlm.nih.gov/pubmed/22369387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200631g
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