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Evaluation of (99m)Tc-Labeled Cyclic RGD Dimers: Impact of Cyclic RGD Peptides and (99m)Tc Chelates on Biological Properties

The main objective of this study is to explore the impact of cyclic RGD peptides and (99m)Tc chelates on biological properties of (99m)Tc radiotracers. Cyclic RGD peptide conjugates, HYNIC-K(NIC)-RGD(2) (HYNIC = 6-hydrazinonicotinyl; RGD(2) = E[c(RGDfK)](2) and NIC = nicotinyl) HYNIC-K(NIC)-3G-RGD(2...

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Autori principali: Zhou, Yang, Kim, Young-Seung, Lu, Xin, Liu, Shuang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310279/
https://ncbi.nlm.nih.gov/pubmed/22369387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200631g
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