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Coligand Effects on Solution Stability, Biodistribution and Metabolism of (99m)Tc-Labeled Cyclic RGDfK Tetramer

In this study, we present the evaluation of two new ternary ligand (99m)Tc complexes [(99m)Tc(HYNIC-tetramer)(tricine)(L)] (L = ISONIC and PDA) as potential radiotracers for tumor imaging. The athymic nude mice bearing the MDA-MB-435 human breast cancer xenografts were used to evaluate their biodist...

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Detalhes bibliográficos
Main Authors: Liu, Shuang, Kim, Young-Seung, Hsieh, Wen-Yuan, Sreerama, Subramanya Gupta
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278016/
https://ncbi.nlm.nih.gov/pubmed/18158950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2007.08.006
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