載入...
Inhibition of Centromere Dynamics by Eribulin (E7389) during Mitotic Metaphase
Eribulin (E7389), a synthetic analog of halichondrin B in Phase III clinical trials for breast cancer, binds to tubulin and microtubules. At low concentrations, it suppresses the growth phase of microtubule dynamic instability in interphase cells, arrests mitosis, and induces apoptosis, suggesting t...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562299/ https://ncbi.nlm.nih.gov/pubmed/18645010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0095 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|