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Intracellular Sodium Regulates Proteolytic Activation of the Epithelial Sodium Channel

Na(+) transport across epithelia is mediated in part by the epithelial Na(+) channel ENaC. Previous work indicates that Na(+) is an important regulator of ENaC, providing a negative feedback mechanism to maintain Na(+) homeostasis. ENaC is synthesized as an inactive precursor, which is activated by...

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Main Authors: Knight, Kristin K., Wentzlaff, Danielle M., Snyder, Peter M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562069/
https://ncbi.nlm.nih.gov/pubmed/18662987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804176200
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