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Intracellular Sodium Regulates Proteolytic Activation of the Epithelial Sodium Channel
Na(+) transport across epithelia is mediated in part by the epithelial Na(+) channel ENaC. Previous work indicates that Na(+) is an important regulator of ENaC, providing a negative feedback mechanism to maintain Na(+) homeostasis. ENaC is synthesized as an inactive precursor, which is activated by...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562069/ https://ncbi.nlm.nih.gov/pubmed/18662987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804176200 |
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