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Enhancement of the CD8(+) T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope

Cytotoxic T lymphocytes are critical for the control of respiratory syncytial virus infection in humans and mice. Recently, we identified a new H-2K(d) restricted subdominant epitope in the RSV M2 protein. In this study, we investigated if modification of anchor residues at positions 2 and 9 in the...

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Main Authors: Mok, Hoyin, Lee, Sujin, Wright, David W., Crowe, James E.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561208/
https://ncbi.nlm.nih.gov/pubmed/18662734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.07.012
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