Signaling through cAMP and cAMP-dependent Protein Kinase: Diverse Strategies for Drug Design

The catalytic subunit of cAMP-dependent protein kinase has served as a prototype for the protein kinase superfamily for many years while structures of the cAMP-bound regulatory subunits have definded the conserved cyclic nucleotide binding (CNB) motif. It is only structures of the holoenzymes, howev...

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Main Authors: Taylor, Susan S., Kim, Choel, Cheng, Cecilia Y., Brown, Simon H.J., Wu, Jian, Kannan, Natarajan
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561045/
https://ncbi.nlm.nih.gov/pubmed/17996741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2007.10.002
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