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Signaling through cAMP and cAMP-dependent Protein Kinase: Diverse Strategies for Drug Design
The catalytic subunit of cAMP-dependent protein kinase has served as a prototype for the protein kinase superfamily for many years while structures of the cAMP-bound regulatory subunits have definded the conserved cyclic nucleotide binding (CNB) motif. It is only structures of the holoenzymes, howev...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561045/ https://ncbi.nlm.nih.gov/pubmed/17996741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2007.10.002 |
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