A carregar...
Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix
Glu230, one of the acidic residues that cluster around the active site of the catalytic subunit of cAMP-dependent protein kinase, plays an important role in substrate recognition. Specifically, its side chain forms a direct salt-bridge interaction with the substrate’s P-2 Arg. Previous studies showe...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253214/ https://ncbi.nlm.nih.gov/pubmed/16253959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051715205 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|