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Expression Levels of the Human DNA Repair Protein Metnase Influence Lentiviral Genomic Integration

We recently identified a Transposase domain protein called Metnase, which assists in repairing DNA double-strand breaks (DSB) via non-homologous end-joining (NHEJ), and is important for foreign DNA integration into a host cell genome. Since integration is essential for productive lentiviral infectio...

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Bibliografski detalji
Glavni autori: Williamson, Elizabeth A., Farrington, Jacqueline, Martinez, Leah, Ness, Scott, O’Rourke, John, Lee, Suk-Hee, Nickoloff, Jac, Hromas, Robert
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556226/
https://ncbi.nlm.nih.gov/pubmed/18549821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2008.05.010
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