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The identification and characterization of the porcine (Sus scrofa) Survival Motor Neuron (SMN1) gene: An animal model for therapeutic studies
Spinal Muscular Atrophy (SMA) is an autosomal recessive disorder that is characterized by the degeneration of the motor neurons of the spinal cord leading to muscle atrophy. SMA is a result of a loss-of-function of the gene SMN1. We have chosen to generate a transgenic swine model of SMA for the dev...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556073/ https://ncbi.nlm.nih.gov/pubmed/18651653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21642 |
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