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The identification and characterization of the porcine (Sus scrofa) Survival Motor Neuron (SMN1) gene: An animal model for therapeutic studies
Spinal Muscular Atrophy (SMA) is an autosomal recessive disorder that is characterized by the degeneration of the motor neurons of the spinal cord leading to muscle atrophy. SMA is a result of a loss-of-function of the gene SMN1. We have chosen to generate a transgenic swine model of SMA for the dev...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556073/ https://ncbi.nlm.nih.gov/pubmed/18651653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21642 |
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