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Disruption of the Survival Motor Neuron (SMN) gene in pigs using ssDNA

Spinal Muscular Atrophy (SMA) is an autosomal recessive neurodegenerative disease that is a result of a deletion or mutation of the SMN1 (Survival Motor Neuron) gene. A duplicated and nearly identical copy, SMN2, serves as a disease modifier as increasing SMN2 copy number decreases the severity of t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Transgenic Res
Prif Awduron: Lorson, Monique A., Spate, Lee D., Samuel, Melissa S., Murphy, Clifton N., Lorson, Christian L., Prather, Randall S., Wells, Kevin D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455718/
https://ncbi.nlm.nih.gov/pubmed/21350916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-011-9496-8
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