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Disruption of the Survival Motor Neuron (SMN) gene in pigs using ssDNA
Spinal Muscular Atrophy (SMA) is an autosomal recessive neurodegenerative disease that is a result of a deletion or mutation of the SMN1 (Survival Motor Neuron) gene. A duplicated and nearly identical copy, SMN2, serves as a disease modifier as increasing SMN2 copy number decreases the severity of t...
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| Publicado no: | Transgenic Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4455718/ https://ncbi.nlm.nih.gov/pubmed/21350916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-011-9496-8 |
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