Composition of the Survival Motor Neuron (SMN) Complex in Drosophila melanogaster

Spinal Muscular Atrophy (SMA) is caused by homozygous mutations in the human survival motor neuron 1 (SMN1) gene. SMN protein has a well-characterized role in the biogenesis of small nuclear ribonucleoproteins (snRNPs), core components of the spliceosome. SMN is part of an oligomeric complex with co...

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發表在:G3 (Bethesda)
Main Authors: Matera, A. Gregory, Raimer, Amanda C., Schmidt, Casey A., Kelly, Jo A., Droby, Gaith N., Baillat, David, ten Have, Sara, Lamond, Angus I., Wagner, Eric J., Gray, Kelsey M.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2018
主題:
Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385987/
https://ncbi.nlm.nih.gov/pubmed/30563832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200874
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