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Structural and mechanistic insights into type II trypanosomatid tryparedoxin-dependent peroxidases
TbTDPX (Trypanosoma brucei tryparedoxin-dependent peroxidase) is a genetically validated drug target in the fight against African sleeping sickness. Despite its similarity to members of the GPX (glutathione peroxidase) family, TbTDPX2 is functional as a monomer, lacks a selenocysteine residue and re...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2552391/ https://ncbi.nlm.nih.gov/pubmed/18522537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080889 |
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