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Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates
Enhancement of the anti-oxidant metabolism of Leishmania parasites, dependent upon the unique dithiol trypanothione, has been implicated in laboratory-generated antimony resistance. Here, the role of the trypanothione-dependent anti-oxidant pathway is studied in antimony-resistant clinical isolates....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428625/ https://ncbi.nlm.nih.gov/pubmed/20553768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.05.015 |
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