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Roles of Trypanothione S-Transferase and Tryparedoxin Peroxidase in Resistance to Antimonials
The clinical value of antimonial drugs, the mainstay therapy for leishmaniasis, is now threatened by the emergence of acquired drug resistance, and a comprehensive understanding of the underlying mechanisms is required. Using the model organism Leishmania tarentolae, we have examined the role of try...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292513/ https://ncbi.nlm.nih.gov/pubmed/18250189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01563-07 |
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