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Structural and mechanistic insights into type II trypanosomatid tryparedoxin-dependent peroxidases

TbTDPX (Trypanosoma brucei tryparedoxin-dependent peroxidase) is a genetically validated drug target in the fight against African sleeping sickness. Despite its similarity to members of the GPX (glutathione peroxidase) family, TbTDPX2 is functional as a monomer, lacks a selenocysteine residue and re...

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Detalhes bibliográficos
Main Authors: Alphey, Magnus S., König, Janine, Fairlamb, Alan H.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2552391/
https://ncbi.nlm.nih.gov/pubmed/18522537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080889
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