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Combination Therapy with Cisplatin and Anti-4-1BB: Synergistic Anti-cancer Effects and Amelioration of Cisplatin-induced Nephrotoxicity

Anti-4-1BB and cisplatin showed synergistic anti-cancer effects in the CT-26 colon carcinoma model, producing complete regression in >60% of mice with either preventive or therapeutic treatment. The tumor-free mice formed long-lasting CD8(+) T-dependent tumor-specific memory. Anti-4-1BB induced r...

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Bibliografiske detaljer
Main Authors: Kim, Young H., Choi, Beom K., Kim, Kwang H., Kang, Sang W., Kwon, Byoung S.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551756/
https://ncbi.nlm.nih.gov/pubmed/18794112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1365
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