4-1BB functions as a survival factor in dendritic cells

4-1BB (CD137) is expressed on dendritic cells (DCs) and its biological function has remained largely unresolved. By comparing 4-1BB-intact (4-1BB(+/+)) and 4-1BB-deficient (4-1BB(-/-)) DCs, we found that 4-1BB was strongly induced on DCs during the maturation, and DC maturation was normal in the abs...

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Bibliografiske detaljer
Main Authors: Choi, Beom K., Kim, Young H., Kwon, Patrick M., Lee, Sang C., Kang, Sang W., Kim, Moon S., Lee, Myoung J., Kwon, Byoung S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681223/
https://ncbi.nlm.nih.gov/pubmed/19299708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800459
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