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4-1BB Signaling Breaks the Tolerance of Maternal CD8(+) T Cells That Are Reactive with Alloantigens
4-1BB (CD137, TNFRSF9), a member of the activation-induced tumor necrosis factor receptor family, is a powerful T-cell costimulatory molecule. It generally enhances CD8(+) T responses and even breaks the tolerance of CD8(+) T cells in an antigen-specific manner. In the present study we found that it...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448654/ https://ncbi.nlm.nih.gov/pubmed/23029041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045481 |
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