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Programmable Oligomers for Minor Groove DNA Recognition

The four Watson-Crick base pairs of DNA can be distinguished in the minor groove by pairing side-by-side three five-membered aromatic carboxamides, imidazole (Im), pyrrole (Py) and hydroxypyrrole (Hp), four different ways. Based on the paradigm of unsymmetrical paired edges of aromatic rings for min...

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Détails bibliographiques
Auteurs principaux: Doss, Raymond M., Marques, Michael M., Foister, Shane, Chenoweth, David M., Dervan, Peter B.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547997/
https://ncbi.nlm.nih.gov/pubmed/16834381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0621795
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