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(S)-4,5-Dihydro-2-(2-hydroxy-4-hydroxyphenyl)-4-methyl-4-thiazolecarboxylic Acid Polyethers: A Solution to Nephrotoxicity

Previous studies revealed that, within a family of ligands, the more lipophilic chelators have better iron-clearing efficiency. The larger the log P(app) value of the compound, the better the iron-clearing efficiency. What is also clear from the data is that although the relative effects of log P(ap...

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Bibliografiske detaljer
Main Authors: Bergeron, Raymond J., Wiegand, Jan, McManis, James S., Vinson, John R. T., Yao, Hua, Bharti, Neelam, Rocca, James R.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547084/
https://ncbi.nlm.nih.gov/pubmed/16640338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0508944
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