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Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection

During acute human immunodeficiency virus type 1 (HIV-1) infection, early host cellular immune responses drive viral evolution. The rates and extent of these mutations, however, remain incompletely characterized. In a cohort of 98 individuals newly infected with HIV-1 subtype B, we longitudinally ch...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Brumme, Zabrina L., Brumme, Chanson J., Carlson, Jonathan, Streeck, Hendrik, John, Mina, Eichbaum, Quentin, Block, Brian L., Baker, Brett, Kadie, Carl, Markowitz, Martin, Jessen, Heiko, Kelleher, Anthony D., Rosenberg, Eric, Kaldor, John, Yuki, Yuko, Carrington, Mary, Allen, Todd M., Mallal, Simon, Altfeld, Marcus, Heckerman, David, Walker, Bruce D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology (ASM) 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546878/
https://ncbi.nlm.nih.gov/pubmed/18614631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01041-08
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