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Use of mchI Encoding Immunity to the Antimicrobial Peptide Microcin H47 as a Plasmid Selection Marker in Attenuated Bacterial Live Vectors
Live attenuated bacterial strains expressing heterologous antigens represent an attractive vaccine development strategy. However, the use of drug resistance genes for the selection of expression plasmids introduced into live vectors poses theoretical health risks. Therefore, we developed a novel app...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
American Society for Microbiology (ASM)
2008
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546845/ https://ncbi.nlm.nih.gov/pubmed/18663003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00487-08 |
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