Progression of Epididymal Maldevelopment Into Hamartoma-like Neoplasia in VHL Disease

Inactivation of the von Hippel-Lindau (VHL) gene and activation of the hypoxia-inducible factor (HIF) in susceptible cells precedes formation of tumorlets and frank tumor in the epididymis of male VHL patients. We performed detailed histologic and molecular pathologic analysis of tumor-free epididym...

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Autors principals: Mehta, Gautam U, Shively, Sharon B, Duong, Heng, Tran, Maxine GB, Moncrief, Travis J, Smith, Jonathan H, Li, Jie, Edwards, Nancy A, Lonser, Russell R, Zhuang, Zhengping, Merrill, Marsha J, Raffeld, Mark, Maxwell, Patrick H, Oldfield, Edward H, Vortmeyer, Alexander O
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546591/
https://ncbi.nlm.nih.gov/pubmed/18813354
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