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Protracted haemangioblastic proliferation and differentiation in von Hippel–Lindau disease

Von Hippel–Lindau (VHL) disease is caused by germline mutation of the VHL tumour suppressor gene. Patients frequently develop multiple nervous system tumours, denominated haemangioblastomas. Analysis of affected autopsy tissues suggests that tumourigenesis propagates from developmentally arrested, e...

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Detalles Bibliográficos
Publicado en:J Pathol
Main Authors: Shively, SB, Beltaifa, S, Gehrs, B, Duong, H, Smith, J, Edwards, NA, Lonser, RR, Raffeld, M, Vortmeyer, AO
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762050/
https://ncbi.nlm.nih.gov/pubmed/18836991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2435
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